MSR main

About the MSRcall home!

Welcome to the MSRcall home! 
  First of all, please allow us to introduce three basic issues about MSRcall home:
  (1) What’s MSR index? MSR is an abbreviation for Methylation Share Rate. MSR index is an epigenetic parameter and it will better reflect the DNA methylation modification level for different regions within genes in animals and plants. 
  (2) How to analyze MSR index? According to the data analysis model of random amplified polymorphic DNA (RAPD) marker (Welsh and McClelland, 1990; Williams et al., 1990), methylated-DNA-fingerprint similarity is generally defined as methylated share rates (MSR). The genetic similarity (S) or methylated share rates (MSR) was determined by Nei and Lynch’s method (Nei and Li, 1979; Lynch, 1990): MSR= 2NAB/(NA + NB), where “NAB” is the number of methylation that colony A and B shared in common, “NA” is the number of methylation in colony A and “NB” is the numbers of methylation in colony B. 
  (3) Who develop the MSRcall? The MSRcall software is a web-based platform for analyses of MSR (methylated share rate) index according to C++ protocol. This MSRcall home is developed by Lan_Liu’ group: Ph.D. Xianyong Lan (From College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China) and Ph.D. Liangliang Liu (From Jiangsu university of Science and Technology). 
Recently three parts are included in the MSRcall home (www.MSRcall.com): (1) MSR Online Computer: A web-based platform for analyses of MSR (methylated share rate) index (an epigenetic parameter reflecting DNA methylation modification level); (2) MSR Download Version: A download version of MSR platform. It can be run in local machine; (3) User Guide for Dowloaded Version of MSR: An instruction manual for MSR.
If you want to know more information about MSR and MSRcall, please search our published paper: “Pan C, Jia W, Wu X, Zhao H, Liu S, Lei C, Lan X*, Chen H. DNA methylation profile of caprine Dnmt3b gene and its influence on growth traits. The Journal of Animal & Plant Sciences, 2013, 23 (2): 380-387”. If you use the MSR for research study, please cite above-mentioned literature. If you use the MSRcall online website to calculate the MSR index, please cite our website: www.msrcall.com. Thanks a lot. 
Any question, please contact  Ph.D. Xianyong Lan (lan342@126.com) and Ph.D. Liangliang Liu(lingyun79626@126.com).

Name	Link	Description
MSR Online Computer	Go to MSR Page	A web-based platform for analyses of Performance Genetics MSR.

MSR Download Version	Click to Download	A download version of MSR platform.It can be run in local machine.

User Guide for Dowloaded Version of MSR	Click to Download	An instruction manual for MSR.
More Calculator	More Tools...	Web-based Tools for Analyses for GADEcall,GDIcall and DALMcall calculator.